泰诺福韦; 替诺福韦;

Product structure (temporary placeholder image)

Category

Intermediates

English Name

Tenofovir

English Synonyms

(R)-PMPA; (R)-9-(2-phosphonomethoxypropyl)adenine; 1-(6-Aminopurin-9-yl)propan-2-yloxymethylphosphonic acid hydrate

CAS No.

147127-20-6; 206184-49-8; 107021-12-5

Molecular Formula

C₉H₁₆N₅O₅P

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Detailed Description

Parameter		Limit
Appearance	:	White or almost white powder
Identification (By HPLC)	:	The retention time of the principal peak in the chromatogram of the sample solution corresponds to that in the obtained chromatogram of the standard solution.
Solubility	:	Slightly soluble in water and practically insoluble in methanol.
Assay (HPLC, on dry basis)	:	98 - 102 %
Unspecified Impurities (HPLC)	:	NMT 1.0 %
Total Impurities (HPLC)	:	NMT 3.0 %
Water Content	:	NMT 6.0 %
Specific Rotation (on dry basis)	:	- 19.00 to - 23.00
CAS number	:	147127-20-6 (anhydous); 107021-12-5 (racemic)

Remarks

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